PUBLICATIONS
Papers
- Hazen, R.M., Griffin, P.L., Carothers, J.M. & Szostak, J.W. Functional information and the emergence of biocomplexity. Proc. Natl. Acad. Sci. 104, 8574-8581.
- Carothers, J.M., Oestreich, S.C. & Szostak, J.W. Aptamers selected for higher-affinity binding are not more specific for the target ligand. J. Am. Chem. Soc. 128, 7929-7937.
- Carothers, J.M., Davis, J.H., Chou, J.J. & Szostak, J.W. Solution structure of an informationally-complex high-affinity RNA aptamer to GTP. RNA. 12: 567-579.
- Plummer, K.A., Carothers, J.M., Yoshimura, M. Szostak, J.W. & Verdine, G.L. In vitro selection of RNA aptamers against a composite small molecule-protein surface. Nucl. Acids Res. 2005, 33: 5602-5610.
- Carothers, J.M., Oestreich, S.C., Davis, J.H. & Szostak, J.W. Informational complexity and functional activity of RNA structures. J. Am. Chem. Soc. 2004, 12: 5130-5137.
- Kopp, E., Medzhitov, R., Carothers, J., Xiao, C., Douglas, I., Janeway, C.A. & Ghosh, S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes & Development. 1999, 13: 2059-2071.
Book chapter
- Carothers, J.M. and Szostak, J.W. In vitro selection of functional oligonucleotides and the origins of biochemical activity. In The Aptamer Handbook: Functional Oligonucleotides and Their Applications (ed. S. Klussmann), chapter 1. Springer-Verlag Press, Berlin: 2006, 3-28.
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