Environmental Biotechnology
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Bioremediation, the treatment of environmental contaminants via biological systems, is an important focus of the laboratory. For the effective and economical use of bioremediation, it is important that we understand the mechanisms of biodegradation and bioaccumulation. Ideally, naturally existing bioremediation processes may be utilized, but these processes must be understood before their potential can be harnessed. Specifically, it is important to determine which factors limit the remediation, and may thus be stimulated, and it is critical to understand the end results of stimulating biological pathways (for example, which byproducts will be produced). We have employed a number of high-throughput techniques to explore the metabolic pathways of bioremediation-relevant model organisms. When natural processes to remediate an environment do not exist or cannot be stimulated, novel pathways may be engineered to accomplish the cleanup task.
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